No evidence for an involvement of copy number variation in ABCA13 in schizophrenia, bipolar disorder, or major depressive disorder.
نویسندگان
چکیده
Institute of Human Genetics, Department of Genomics, Life and Brain Center, Institute for Genomic Mathematics, Department of Psychiatry, University of Bonn, German Center for Neurodegenerative Diseases (DZNE), Bonn, Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, University of Heidelberg, Mannheim, Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Molecular and Clinical Neurobiology, Department of Psychiatry, Ludwig-Maximilians University, Munich, Department of Psychiatry, University of Halle-Wittenberg, Halle, Section of Psychiatric Genetics, Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August University, Göttingen, Germany, Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organisation of the Brain, Genomic Imaging, Research Centre Juelich, Juelich, Germany and Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA
منابع مشابه
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression.
Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of approximately 80% indicating a substantial genetic component. Population genetics and genome-wide association studies suggest an overlap of genetic risk factors between these illnesses but it is unclear how this genetic component is divided between common gene polymorphisms,...
متن کاملMulti-factorial Etiology of Bipolar Disorder and Schizophrenia in Iran: No Evidence of Borna Disease Virus Genome
ABSTRACT Background and Objectives: Psychiatric disorders such as schizophrenia and bipolar disorder pose a high burden among the general population. Etiological factor(s) of such disorders remain unknown. Borna disease virus (BDV) is a neurotropic virus that has been suggested as an etiological agent for psychiatric disorder...
متن کاملToxoplasmosis and its Relationship with Various Mental Disorders
Toxoplasmosis is a globally distributed disease caused by a parasitic protozoan called Toxoplasma gondii (T. gondii) in humans and animals that often develops asymptomatic acquired infections but the important aspect of this parasitic infection is the possible risk of congenital transmission and its severe effects on the fetus such as hydrocephalus, microcephaly, deafness and abortion up to mil...
متن کاملA Comparison of Selective Attention Processing in Major Depressive Disorder and Schizophrenia
Objective: Cognitive deficits play an important role in differential diagnostics, prognosis and rehabilitation of people with psychological disorders. Attention problems have profound impact on the therapeutic response, risk of relapse, function and quality of life in people with major depressive disorder and schizophrenia. This study compared selective attention of people with schizophrenia, M...
متن کاملA Comparison of Emotional Schemas in Patients with Bipolar Disorders and Major Depressive Disorder in Remission and Nonclinical Population
Objective: Similarities and differences among mood disorders can help psychiatrics in their exact diagnosis and more effective treatments. Therefore, the current research sought to identify differences between patients with bipolar disorder, major depressive disorder, and nonclinical group in emotional schemas. Methods: The present research was a cross-sectional study. The research sample cons...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Psychiatric genetics
دوره 23 1 شماره
صفحات -
تاریخ انتشار 2013